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b12 deficiency


Splash77

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..ive been reading about b12 deficiency, does anyone know the correct blood level's in australia? because after going to the doctor's to be checked i was told i was ok with a reading of 190 pg/ml. I know in the uk/europe if its under 500 pg/ml you need to have injection's...does anyone have any knowledge of this.

cheers...

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Guest haunted1234

I have pernicious anaemia and have B12 approximately every 2-3 months. not sure on the blood levels though sorry. However, my prescription was $20 and that was for 9 months worth of jabs which i thought was very reasonable. speak to your GP, as it's something you cant do without if you're deficient. signs and symptoms are usually a tell tale sign though.

 

i know when i need a jab as i feel lethargic, nauseous, my memory is shocking, headaches etc. there is a website for pernicious anaemia im sure they would be able to help. Good Luck x

 

it can also effect your liver enzymes...as id gone a while undiagnosed my doc said i had the liver of an alcoholic!

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I have pernicious anaemia and have B12 approximately every 2-3 months. not sure on the blood levels though sorry. However, my prescription was $20 and that was for 9 months worth of jabs which i thought was very reasonable. speak to your GP, as it's something you cant do without if you're deficient. signs and symptoms are usually a tell tale sign though.

 

i know when i need a jab as i feel lethargic, nauseous, my memory is shocking, headaches etc. there is a website for pernicious anaemia im sure they would be able to help. Good Luck x

 

it can also effect your liver enzymes...as id gone a while undiagnosed my doc said i had the liver of an alcoholic!

cheers for the reply...i will speak my GP again and see what they say.

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Just a thought, but are you sure of your units here? it's possible one country measures in picomoles/volume rather than picograms/volume which could explain the discrepancy in values.

 

not sure really but i would be interested in finding out if it is measured the same or not...

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Just found the conversion factor 1.35 pg/ml = 1 pmol/l

 

according to the bmj:

Generally, serum vitamin B12 can be broken down into 3 values:

 

 

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Guest The Pom Queen

I can't do it now but I will have lots of blood results somewhere as I am B12 deficient, it would take forever to go through all my notes though, but if no one can help I will have a look through and see what I can find.

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Guest The Pom Queen

Just found this which may be interesting, but it shows that only your Dr can really advise on what your results should be.

 

Some info on Lab ranges used for normal b12 serum in different countries :

 

Germany : 200 - 1000ng/l 148 - 738pmol/l .

recommended form of B12 treatment: Hydroxocobalamin

-----------------------------------------------------------------------------------

In UK : Apparently national ?normal? B12 serum levels for UK are: 138 - 780 pmol/ L.

 

But different labs use different machines and different units etc, some info:

 

Bas/ Hants hospital, 2006: 161 - 531 ng/L = 119 - 392 pmol/ L

Frimley Park lab range for normal: serum B12 : 220-900 ng/L

IDWL serum B12 180-914 pg/ml

recommended form of B12 treatment: Hydroxocobalamin, cyanocobalamin ia also available, all only with perscription.

 

---------------------------------------------------------------------------------

New Zeeland : 93-730 pmol / L

 

Auckland:

Normal reference interval = 170-800 pmol/L;

The borderline range of undetermined clinical significance is 110 - 170 pmol/L.

 

Recommended form of B12 treatment: Hydroxocobalamin Cyanocobalamin is also widely prescribed

Leaflet:

http://www.medsafe.govt.nz/Profs/Datash ... meninj.htm

 

 

----------------------------------------------------------------------------------

Canada : 200-1000 pg/ml = 148-738 pmol/l

recommended form of B12 treatment: Cyanocobalamin

2008: Canada is now 198 to 615 pmol/L or 146 pg/mL to 453 pg/mL.

--------------------------------------------------------------------------------

 

USA: 180 - 914 pg/ml

Recommended form of B12 treatment: Hydroxocobalamin, and or Cyanocobalamin

 

New Jersey USA: 211 (units?)and 800 (units?).

 

-----------------------------------------------------------------------------------

Spain : 160 - 1160 ?

recommended form of B12 treatment: Cyanocobalamine.

All meds available over the counter.

 

----------------------------------------------------------------------------------

Australia: 100 - 700 pmol / L lab #1 (4 labs in Aust)

140 - 650 pmol/L (Melbourne Pathology)

150 - 700 pmol/L (Dorevitch Pathology)

 

recommended form of B12 treatment: Hydroxocobalamin, cyanocobalamin also available, all over the counter.

------------------------------------------------------------------------------

 

Netherland: 150-700 pmol/l

But individual cities/ towns/ hospitals use different values, ie:

Groningen 130-800 pmol/l

Leiden 150-750 pmol/l

recommended form of B12 treatment: Hydroxocobalamin, on perscription only.

------------------------------------------------------------------------------

 

Japan :lower level of 525 pmoL or lower level is 700 and upper level is 1300?

recommended form of B12 treatment: Methylcobalamin?

-----------------------------------------------------------------------------------

 

Ireland

recommended form of B12 treatment: Was Cyanocobalamin, now Hydroxocobalamin.

Northern Ireland:

ref range for normal: 158 - 1050 ng/L

Other lab uses: 240-900 (units?)

 

 

---------------------------------------------------------------------------

 

France: 133-675 pmol/l of 180-914 ng/l lab. Pasteur in Paris

recommended form of B12 treatment: Cyanocobalamin and

Hydroxocobalamin available over the counter.

 

-------------------------------------------------------------------------

 

Switzerland: 150 - 700 pmol/l

 

------------------------------------------------------------------

Hong Kong :

193-982 pg/mL or 142-725 pmol/L

 

------------------------------------------------------

 

conversions

pmol/l x 1.3553 = pg/mL

pg/mL x 0.7378 = pmol/L

_____________________________________________________________

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I can't do it now but I will have lots of blood results somewhere as I am B12 deficient, it would take forever to go through all my notes though, but if no one can help I will have a look through and see what I can find.

 

thats ok dont go to all that trouble...but thanks very much anyway...i think ill just go and eat a whole cabbage for me dinner that

should cure it...or is that low iron...

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Just found this which may be interesting, but it shows that only your Dr can really advise on what your results should be.

 

Some info on Lab ranges used for normal b12 serum in different countries :

 

Germany : 200 - 1000ng/l 148 - 738pmol/l .

recommended form of B12 treatment: Hydroxocobalamin

-----------------------------------------------------------------------------------

In UK : Apparently national ?normal? B12 serum levels for UK are: 138 - 780 pmol/ L.

 

But different labs use different machines and different units etc, some info:

 

Bas/ Hants hospital, 2006: 161 - 531 ng/L = 119 - 392 pmol/ L

Frimley Park lab range for normal: serum B12 : 220-900 ng/L

IDWL serum B12 180-914 pg/ml

recommended form of B12 treatment: Hydroxocobalamin, cyanocobalamin ia also available, all only with perscription.

 

---------------------------------------------------------------------------------

New Zeeland : 93-730 pmol / L

 

Auckland:

Normal reference interval = 170-800 pmol/L;

The borderline range of undetermined clinical significance is 110 - 170 pmol/L.

 

Recommended form of B12 treatment: Hydroxocobalamin Cyanocobalamin is also widely prescribed

Leaflet:

http://www.medsafe.govt.nz/Profs/Datash ... meninj.htm

 

 

----------------------------------------------------------------------------------

Canada : 200-1000 pg/ml = 148-738 pmol/l

recommended form of B12 treatment: Cyanocobalamin

2008: Canada is now 198 to 615 pmol/L or 146 pg/mL to 453 pg/mL.

--------------------------------------------------------------------------------

 

USA: 180 - 914 pg/ml

Recommended form of B12 treatment: Hydroxocobalamin, and or Cyanocobalamin

 

New Jersey USA: 211 (units?)and 800 (units?).

 

-----------------------------------------------------------------------------------

Spain : 160 - 1160 ?

recommended form of B12 treatment: Cyanocobalamine.

All meds available over the counter.

 

----------------------------------------------------------------------------------

Australia: 100 - 700 pmol / L lab #1 (4 labs in Aust)

140 - 650 pmol/L (Melbourne Pathology)

150 - 700 pmol/L (Dorevitch Pathology)

 

recommended form of B12 treatment: Hydroxocobalamin, cyanocobalamin also available, all over the counter.

------------------------------------------------------------------------------

 

Netherland: 150-700 pmol/l

But individual cities/ towns/ hospitals use different values, ie:

Groningen 130-800 pmol/l

Leiden 150-750 pmol/l

recommended form of B12 treatment: Hydroxocobalamin, on perscription only.

------------------------------------------------------------------------------

 

Japan :lower level of 525 pmoL or lower level is 700 and upper level is 1300?

recommended form of B12 treatment: Methylcobalamin?

-----------------------------------------------------------------------------------

 

Ireland

recommended form of B12 treatment: Was Cyanocobalamin, now Hydroxocobalamin.

Northern Ireland:

ref range for normal: 158 - 1050 ng/L

Other lab uses: 240-900 (units?)

 

 

---------------------------------------------------------------------------

 

France: 133-675 pmol/l of 180-914 ng/l lab. Pasteur in Paris

recommended form of B12 treatment: Cyanocobalamin and

Hydroxocobalamin available over the counter.

 

-------------------------------------------------------------------------

 

Switzerland: 150 - 700 pmol/l

 

------------------------------------------------------------------

Hong Kong :

193-982 pg/mL or 142-725 pmol/L

 

------------------------------------------------------

 

conversions

pmol/l x 1.3553 = pg/mL

pg/mL x 0.7378 = pmol/L

_____________________________________________________________

 

Thanks for that..ill have a nose at it now...

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