If your employment is related to your nominated occupation, then you should pick yes. For me, I only included the employment after 2016 in EOI and didn't mention about earlier employment in EOI. However, I mentioned all the employments while lodging visa.
I was doing everything myself, so I had no idea about this issue previously. But, I think in EOI, there is a section where you can split the date of your employment and pick them as related and not related.
Hope this helps.